The reaction mechanism occurs with the formation of an imine, which can be isolated or hydrolyzed to form the final ketone.
Mechanism for acid hydrolysis of imine:
Reaction of nitriles with organometallics
- Details
- Germán Fernández
- NITRILE THEORY
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The nitriles react with organometallic lithium or magnesium, to form ketones, after an acid hydrolysis step.
