The DIBAL has the following structure:
Reaction Mechanism:
Cyclic esters (lactones) reduce with DIBAL to give molecules with aldehyde and alcohol groups.
Reduction of esters to aldehydes: DIBAL
- Details
- Germán Fernández
- ESTERS THEORY
- Hits: 43743
Esters are reduced to aldehydes with diisobutylaluminum hydride (DIBAL) at -78°C. A single equivalent must be used to stop the reaction in the aldehyde, avoiding its reduction to alcohol.
