In this synthesis, the phthalimide salt is reacted with the halogenated malonic ester. In later stages it is alkylated, hydrolyzed and decarboxylated, obtaining the amino acid.

deprotonation of phthalimide.
nucleophilic substitution
deprotonation of the diester
Hydrolysis of imide and diester
Decarboxylation of 1,3-diacid.

No thoughts on “Amino Acid Synthesis - Gabriel”