Cross-coupling of alkynylsilanols with aryl halides promoted by potassium trimethylsilanolate

Scott E. Denmark and Steven A. Tymonko
Roger Adams Laboratory, Department of Chemistry University of Illinois, Urbana, Illinois 61801, Email: denmarkscs.uiuc.edu
SE Denmark, SA Tymonko, J. Org. Chem., 2003, 68, 9151-9154.

Summary:
Palladium catalyzes the cross-coupling of aliphatic alkynylsilanols with aryl iodides at room temperature in good yields. Coupling is promoted by potassium trimethylsilanolate and copper(I) iodide as a cocatalyst.