SUBJECT 1. CARBOXYLIC ACIDS

Theory: Nomenclature of carboxylic acids | Physical properties of carboxylic acids | Acidity and basicity of carboxylic acids | Preparation of carboxylic acids | Oxidation of alcohols and alkenes | Organometallic compounds | Hydrolysis of nitriles | Preparation of Alkanoyl Halides | Preparation of anhydrides | Synthesis of esters from carboxylic acids | Synthesis of amides from carboxylic acids | Reaction with organometallics of carboxylic acids | Reduction to alcohols of carboxylic acids | Carboxylic acid enolates | Hell-Volhard-Zelinski | Hunsdieker reaction of carboxylic acids

Problems: Carboxylic Acid Problems 

SUBJECT 2. DERIVATIVES OF CARBOXYLIC ACIDS

Order of reactivity | Acid-base behavior

• ALKANOYL HALIDES 

Theory:  Alkanoyl Halide Nomenclature | Reaction with water and alcohols of alkanoyl halides | Reaction with amines of alkanoyl halides | Reaction with organometallics of alkanoyl halides | Reduction to alcohols and aldehydes of alkanoyl halides

Problems: Acid Halide Problems

• ANHYDRIDES

Theory:  Anhydride Nomenclature | Anhydride Reactivity

• ESTERS

Theory:  Nomenclature of esters | Hydrolysis of esters | Transesterification of esters | Amides from esters | Reaction with organometallic esters | Reduction to alcohols and aldehydes of esters | Ester enolates | Claisen condensation of esters | pyrolysis of esters

Problems : Esters Problems

• AMIDES

Theory:  Amide nomenclature | Amide hydrolysis | Reduction to amines and aldehydes of amides | Amide enolates and amidates | Hofmann rearrangement of amides

Problems:  Amide Problems

• NITRILES

Theory:  Nitrile nomenclature | Acidity and basicity | Hydrolysis of nitriles | Reaction with organometallic nitriles | Reduction of nitriles to amines and aldehydes.

Problems: Nitrile problems

SUBJECT 3. DIFUNCTIONAL COMPOUNDS

Theory:  Acetylacetic synthesis | Malonic synthesis | Knoevenagel condensation | Michael's addition

SUBJECT 4. AMINES

Theory:  Amine nomenclature | Physical properties and acid base of amines | Amine synthesis | Reductive Amination of Amines | Amine reactivity | Hofmann elimination of amines | Mannich reaction of amines | Removal of Cope from amines | Reaction with nitrous acid of amines | Diazomethane

Problems: Amine problems

UNIT 5. SILICON, PHOSPHORUS AND SULFUR COMPOUNDS

Theory: Phosphorus Compounds | Wittig reaction | Wadsword_Emmons | Horner-Wittig | Sulfur compounds |Thiols | Sulfides | Sulfoxide removal | Sulfur ylides | Thioacetals | Synthesis of 1,3-dithianes | silicon compounds

SUBJECT 6. STEREOCHEMISTRY II

Theory: Types of isomers | Conformational isomers | Symmetry elements | Symmetry axis | Reflection plane | Center of symmetry | Alternating axis | Elements of asymmetry | chiral center | Chirality axis | Chirality plane | Helical molecules | Notations | Prochirality | Types of ligands | Pro_R and Pro_S ligands | Faces | Racemate resolution