The tosylhydrazones of aldehydes or ketones [1] react with two equivalents of organolico generating an anionic intermediate [2] capable of undergoing alkylation processes.

Mechanism:

Examples of organic synthesis using the Shapiro reaction.

The tosylhydrazones of aldehydes or ketones [1] react with two equivalents of organolico generating an anionic intermediate [2] capable of undergoing alkylation processes.