Reaction of nitriles with organometallics
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Germán Fernández
NITRILE THEORY
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The nitriles react with organometallic lithium or magnesium, to form ketones, after an acid hydrolysis step.
The reaction mechanism occurs with the formation of an imine, which can be isolated or hydrolyzed to form the final ketone.
Mechanism for acid hydrolysis of imine: