ISSUE:

I am looking for the mechanism of this reaction 11 months 1 week before #13843

meric topic author Out of line Expert Browser messages: 150 Thanks received: 13	Good afternoon, the C alpha between the 2 carbons is more reactive than the C alpha of the first carbonyl, I am looking for a reaction mechanism to deprotonate this C alpha and then an SN, see the attached Regards Attachments:
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wilbertrivera Out of line Moderator Messages: 1621 Thanks received: 361	Hello Forero: It corresponds to use a strong bulky base, such as LDA, to abstract a hydrogen from the alpha carbon of the ketoester and then with this nucleophile, react on a 1-halide-2-butene. Regards
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