The Barbier reaction makes it possible to obtain unstable organometallic reagents in the reaction medium. Initially it was carried out with Magnesium metal, generating magnesium in situ. Later it was extended to other metals: Sn, Zn..., being able to work in aqueous media, without requiring the protection of acid groups (hydroxyls).

babier reaction 01

The mechanism of formation of the organometallic occurs by transfer of electrons from the metal to the haloalkane.

babier reaction 15

The mechanism of formation of the organometallic occurs by transfer of electrons from the metal to the haloalkane.

babier reaction 02