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Propose mechanism- Selective transformation 7 years 4 months before #9553

Hello again, I need to propose a mechanism for the following reaction by selective transformation, I attach the image


I hope you can help me, thank you very much!
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Last Edition: by MarianaHA .

Propose mechanism- Selective transformation 7 years 4 months before #9566

Hi Mariana.
I present an alternative to carry out the transformation that you suggest, for this I resort to a chemoselective reaction of a ketone in the presence of an aldehyde. On the other hand, the greater reactivity of the aldehyde is used to form an epoxide with a sulfur ylide and finally 2 eq of a Grignard are used to open the epoxide. One eq is consumed by the presence of OH, coming from the reduction of the ketone and the other manages to open the epoxide to form the alcohol.



Greetings ;)
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Last Edition: by Wilbertrivera . Reason: improve writing

Propose mechanism- Selective transformation 7 years 4 months before #9567

Thank you so much!

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