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Mechanism of the Skraup reaction 1 year 10 months ago #13122

Good morning,
I have been seeing different variants of this reaction and the explanations are really lame, does anyone know a link with a detailed explanation?
The last one from wikipedia based on 1,2,3-propanetriol as the starting product, the explanation of the mechanism is quite poor, there are many gaps, at one point there is a 2 propenol with a formal charge +1 in the C ipso but they tell me that benzoamine attacks with its 2 e the beta position of alcohol, there are no detailed and well-argued explanations of the mechanism anywhere.
Since quinoline and isoquinoline are starting points for many forms and other substances, it is an important topic to delve into this type of molecules. All the best

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Mechanism of the Skraup reaction 1 year 10 months ago #13130

Hello, you can see the mechanism at this address: www.quimicaorganica.org/quinolina-e-isoq...inolinas-skraup.html

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