ISSUE:

Mayte sends me this email:

{quote}Hello, I need to do a synthesis of m-nitrobenzaldehyde dimethylacetal, and I don't even know where to start, since I don't know how to formulate dimethylacetal,... I don't know if you could help me, but I have I have to deliver a prescription and I'm pretty lost. Greetings and thanks.{/quotes}

m-nitrobenzaldehyde [1] reacts with two equivalents of methanol in a sulfuric medium to form the dimethyl acetal of m-nitrobenzaldehyde [2].

You can see the mechanism at the following address:

www.quimicaorganica.org/aldehidos-y-ceto...ion-de-acetales.html

Hello!

Excuse me, I'm trying to prepare the compound 3 nitrobenzaldehyde from benzene, but I don't know what to do first, whether to introduce the aldehyde with the Gatternankoch reaction or nitrate first.

I really appreciate the help!

Please!

Hello, to obtain the 3-nitrobenzaldehyde you must nitrate the benzaldehyde.

The synthesis of benzaldehyde from benzene can be carried out in different ways: 1/ Gatterman-Koch reaction, 2/ Controlled oxidation of toluene, among other possibilities. Greetings