Acyloin condensation transforms esters [1] into alpha-hydroxyketones [2]. This reaction is carried out with sodium metal in an inert solvent.
intramolecular acyloin
Organic Chemistry Book
Organic Nomenclature Book
THE MOST READ
- Alkanes nomenclature
- Isomer classification
- Physical properties of alkanes
- Geometric or cis-trans isomers
- Types of hydrocarbons
- isomeric alkanes
- The 20 amino acids that make up proteins
- Alkene Nomenclature
- Alkanes
- Alcohol Nomenclature
- Alcohols - general characteristics
- Physical properties of ethers
- Alcohol oxidation
- Cycloalkanes nomenclature
- Molecular chirality and enantiomers
- Benzene nomenclature
- Anhydride Nomenclature
- Physical properties of Alkynes
- Amino Acids - Isoelectric Point
- Newman projection
- Synthesis of Carboxylic Acids
- Amine Nomenclature
- Alkene Hydration
- Nomenclature - Carboxylic Acids
- optical activity
- Fisher projection
- Alkenes hydrogenation
- Physical Properties of Alkenes
- Ozonolysis of Alkenes
- Enantiomer nomenclature
- Benzene Nitration
- Synthesis of Alkenes by Dehydration of Alcohols
- Physical properties of amines
- degree of unsaturation
- conformational isomers
- Sulfonation of benzene
- Acidity and basicity of alcohols
- Physical Properties of Carboxylic Acids
- Conformational analysis of ethane
- Electrophilic addition reactions
- Synthesis of esters from carboxylic acids - Esterification
- Stereochemistry - Stereoisomerism
- Alkyne nomenclature
- aldol condensation
- Isomers with a single asymmetric carbon
- Williamson's synthesis of ethers
- Haloform (Iodoform) reaction
- halogenation of benzene
- Synthesis of ethers by condensation of alcohols
- Ethers - epoxides nomenclature
- Symmetry in Chiral Molecules: Meso Forms
- Markovnikov Rule - Regioselectivity
- alkynes
- Halogenation of Alkynes
- Synthesis of Alcohols by reduction of carbonyls
- Alkene polymerization
- RS Notation on Fischer Projection
- Halogen addition
- Alkyne hydrogenation
- Alkyne Hydration
- Passage from Newman to Fischer
- Formation of Alkoxides from Alcohols
- Easel Projection
- Butane conformational analysis
- Electrophilic Aromatic Substitution
- Acidity and Basicity of Carboxylic Acids
- Synthesis of Alkynes by Alkylation
- Ring Strain in Cycloalkanes
- Synthesis of Alcohols by Hydration of Alkenes
- Alkyne Acidity
- Synthesis of Alcohols from Haloalkanes
- Synthesis of amides from carboxylic acids
- Alkene Epoxidation
- Addition of Hydrogen Halides to Alkynes
- Alkenes - Structure and Bond
- Alkenes
- HBr addition with peroxides
- Cross or mixed aldol condensation
- Acid-Base Properties of Amines
- Structure and bonding of amines
- Unimolecular elimination - E1
- Alkene Stability
- cyclohexane
- HX addition
- Benzene - Protection and deprotection of the amino group
- Conformations of Cyclohexane
- Synthesis of Anhydrides from Carboxylic Acids
- Hydroboration of Alkenes
- Structure and bonding in ethers and epoxides
- cyclopropane
- Reaction of anhydrides with water
- Halohydrin formation
- Substitution/elimination competition
- Lactone Synthesis
- Alkyne Ozonolysis
- Synthesis of Alkenes by E2
- Reduction of carboxylic acids to alcohols
- cyclobutane
- Synthesis of alpha, beta-unsaturated carbonyls
- Hofmann elimination
FORUM: LAST POST
-
-
- Doubt Activators, which one is stronger?
- In: Organic Chemistry I / Benzene
- 8 hours 53 minutes ago
-
-
-
- Intramolecular condensation + transposition? is ...
- In: Organic Chemistry I / Aldehydes and ketones
- 8 hours 55 minutes before
-
-
-
- cause dell'odore della paraffin
- In: Unclassified topics / Miscellaneous issues
- 2 days 23 hours before
-
-
-
- Aid
- In: Organic Chemistry II / Phosphorus, Silicon and Sulfur
- 5 days 4 hours before
-
-
-
- ketamine synthesis
- In: Organic Chemistry II / Amines
- 6 days 3 hours before
-
-
-
- Phosphorus ylide formation reaction
- In: Organic Chemistry II / Derivatives of Acids
- 6 days 6 hours before
-
-
-
- Methanol in fruit wine.
- In: Organic Chemistry I / Alcohols and ethers
- 6 days 17 hours before
-
-
-
- Doubt reaction of knoevenagel and michael + nitroeten...
- In: Organic Chemistry I / Aldehydes and ketones
- 6 days 18 hours before
-
-
-
- Doubt Electronic Configuration Mn
- In: Organic Chemistry I / Introduction to Organic Chemistry
- 1 week 22 hours before
-
-
-
- Drawings with ChemDraw
- In: Molecular Editors / Chemdraw
- 1 week 1 day before
-
-
-
- Doubt Enolates - nucleophile atom - alkylation
- In: Organic Chemistry I / Aldehydes and ketones
- 1 week 3 days before
-
-
-
- Pummerer rearrangement
- In: Organic Chemistry II / Phosphorus, Silicon and Sulfur
- 1 week 4 days before
-
-
-
- reactions
- In: Organic Chemistry II / Phosphorus, Silicon and Sulfur
- 1 week 5 days before
-
-
-
- Synthesis of 2 compounds with sulfonation
- In: Advanced Organic Chemistry / Organic Synthesis
- 3 weeks 7 hours before
-
-
-
- phenanthyl
- In: Unclassified topics / Miscellaneous issues
- 3 weeks 22 hours before
-
-
-
- How to get cyclohexylbenzene?
- In: Organic Synthesis / Questions about Retrosynthesis and Synthesis
- 3 weeks 1 day before
-
LATEST NEWS
- Benzene - Problem 16
- azo coupling
- Sandmeyer and Schiemann reactions
- Claisen transposition
- birch reduction
- Side chain oxidation
- The benzylic position
- Aromatic nucleophilic substitution by addition-elimination
- Protection of activated positions
- Reduction of nitro to amino and oxidation of amino to nitro
- Synthesis of 1,2-dicarbonyl compounds
- Synthesis of 1,3-dithianes
- benzoin condensation
- acyloinic condensation
- Knoevenagel condensation
- Michael's addition
- Review of Claisen condensation
- helical molecules
- Rp and Sp notation in planes of chirality
- Ra/Sa notation on chirality axes
- R/S notation in stereogenic centers
- Elements of asymmetry leading to chiral molecules
- Elements of symmetry leading to achiral molecules
- conformational analysis
- Molecular structure
- Phosphines and phosphorus ylides
- Synthesis of 1,3-dithianes. UMPOLUNG reactions
- Thioacetals, hydrolysis and reduction to alkanes
- ylides of sulfur
- Sulphoxide removal WITHOUT
- The Thioethers
- thiols
- simulation of the infrared spectrum of propanamide
- Simulation of the infrared spectrum of 1-butanamine
- Simulation of the infrared spectrum of ethyl ethanoate
- Simulation of the infrared spectrum of ethanoyl chloride
- Simulation of the infrared spectrum of propanoic acid
- Simulation of the infrared spectrum of ethanenitrile
- Simulation of the infrared spectrum of diethyl ether
- Simulation of the infrared spectrum of ethanal
- Simulation of the infrared spectrum of 2-butanone
- Simulation of the infrared spectrum of 1-propanol
- Guareschi-Thorpe synthesis of pyridine
- Kröhnke synthesis of pyridine
- Pomerantz-Fritsch synthesis of isoquinolines
- Pictet Spengler synthesis of isoquinoline
- Bischer–Napieralski synthesis
- Friedlander quinoline synthesis
- Combes synthesis of quinolines
- Alkyl and vinyl quinolines and isoquinolines
- Nucleophilic substitution in quinoline and isoquinoline
- Nucleophilic addition to quinolines and isoquinolines
- Lithiation reaction in quinoline and isoquinoline
- Electrophilic substitution by N-oxides
- Electrophilic substitution reaction in quinoline and isoquinoline
- Reactions with nitrogen lone pair: quinoline and isoquinoline
- Reactivity of alkyl and vinyl pyridines
- Nucleophilic substitution by elimination-addition: the pyridine
- Nucleophilic substitution reactions in pyridine
- Nucleophilic addition reactions to pyridines
- pyridine lithiation
- Electrophilic substitution at position 4 of pyridine
- Synthesis of thiophene by 1,3-dipolar
- Paal–Knorr synthesis of thiophene
- Furan synthesis by 1,3-dipolar
- Feist-Benary synthesis of furan
- Paal–Knorr synthesis of furans
- Synthesis of pyrrole via 1,3-dipolar
- Hantzch synthesis of pyrrole
- Paal–Knorr synthesis of pyrrole
- furan opening
- Derivatives of pyrrole, thiophene and furan
- Cycloaddition reactions in furan
- Lithiation reaction
- Nucleophilic substitution in pyrrole, thiophene and furan
- nucleophilic addition
- Electrophilic substitution on thiophene
- Sulfonation, formylation, Mannich and acetylation of furan
- Madelung synthesis of indole
- Fisher's synthesis of indole
- Indole ring reduction
- Indole ring expansion
- Indole derivatives
- Electrophilic substitution with position 3 of the indole occupied
- Electrophilic substitution at the indole
- indole acidity
- Examples of fused heterocycle nomenclature
- Literation of the base heterocycle and numbering of the annex
- Peripheral numbering of the global heterocycle
- Rules for the choice of the base component
- General concepts of condensed heterocycle nomenclature
- General characteristics of diazines
- Cyclization of carbenes nitrenes and radicals
- Cyclization on sp carbons
- Cyclization processes by nucleophilic addition and addition-elimination at sp¹²2 carbons
- Formation of cycles through S$_N$2
- Classification of nucleophilic attacks (Baldwin's Rules)
- Reactants in cyclization reactions
- Synthesis of heterocycles by cyclization reactions
- The anomeric effect